Radiommenolysis

Radiommenolysis is a therapeutic method of Nuclear Medicine.

It is applied for the treatment of chronic arthritis of all joints, except for the spine.

The point of action of this treatment is hymenitis, where the pathophysiology of the immunobiological etiology of arthritis is focused, as a result of the symptomatology of the disease.
The action of Radiommenolysis is based on selective irradiation of the articular membrane with specific radiopharmaceuticals administered intra-articularly.

Depending on the case of each patient, radiopharmaceuticals are used, taking into account the radial range required therein.
The radiopharmaceuticals used are: Y 90, Re 186 and Er 169.

Most Common Applications :

• Rheumatic diseases
• Osteoarthritis
• Αrthritis with fluid collection
• Chronic inflammation after knee arthroplasty
• Haemophilia arthritis
• Hymenitis

How It Works :

• The radiopharmaceutical is administered to the affected joint and then the joint is immobilized.
• During the action of radiopharmaceuticals, the inflammation due to immunosuppression decreases, without burdening the cartilage, bones and the rest of the body, as the radiopharmaceuticals have a small radial range.
• Then, weeks later, the inflamed membrane begins to shrink, and the symptoms of arthritis subside.
• Finally, the improvement in the symptoms of arthritis occurs in about one month.

A key prerequisite for a good outcome is complete clinical and laboratory testing to assess whether arthritis is appropriate for this treatment, as well as to make the correct choice of the radioisotope.

Results of treatment

Results depend on the type of arthritis and the degree of joint degeneration.
The best results are reported in rheumatoid arthritis with symptoms up to 80% In osteoarthritis up to 50% or even 80% of patients.

Side Effects – Complications – Contraindications:

• Transient exacerbation of arthritis may occur due to radiation irritation.
• Also, due to immobilisation of the joint during treatment of the lower extremities, there is a risk of thrombophlebitis.
• The absolute contraindication for the application of Radiommenolysis is pregnancy and young age.

Literature exists in prestigious scientific journals